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Doxycycline and lactic acid bacillus capsules for acne. This medication is not indicated for use in patients under the age of 12 years. Drug/Device Interactions The following drug/device interactions have been identified. Based on the potential drug interaction(s) listed below, the and/or device should be discontinued at the first sign of an apparent interaction. Antifungal agents: agents can decrease the absorption or metabolism of azole antifungals. antifungal agents should be used at 1-2x the usual dose in patients on an antifungal agent or with concomitant use of an antifungal drug. Clindamycin: Clindamycin may inhibit or decrease the metabolism of azole antifungals and should be used with caution when in connection azole antifungals. Corticosteroids (exemplified): are inducers of steroid enzymes, which can cause significant decreases in plasma cytochrome P-450 levels. Inhibition of activity is expected when concomitant use with cyclosporine or doxazosin is contemplated. Corticosteroids also may increase the blood coagulation, so treatment with corticosteroids should be limited to a maximum of 25 percent the scheduled maintenance dose. Chloracne: Azoles (including azole-sensitizing agents and azole-antifungal agents) chloracne should be used at the lowest effective dose in patients with severe